Article
Navigating the body of literature assessing BRCA1/2 mutations and markers of ovarian function: a systematic review and meta-analysis.
Journal of assisted reproduction and genetics - 1 May 2020
Cordeiro Mitchell Christina N, McGuinness Bailey, Fine Eliana, Kearns William G, Christianson Mindy S, Segars James, Pastore Lisa M
Abstract excerpt
PURPOSE: Twelve percent of women in the USA will develop invasive breast cancer in their lifetime, and that risk increases to 80% if they carry a BRCA1 or BRCA2 mutation. BRCA1/2 mutations are thought to potentially affect ovarian reserve and/or fertility. METHODS: PubMed and PubMed Central were searched for publications on ovarian reserve-related outcomes (i.e., AMH and response to controlled ovarian...
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