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Article

BRCA1/2 genes mutations, ovarian reserve and female reproductive outcomes: a systematic review of the literature.

Minerva ginecologica - 1 Oct 2020

Merlino Lucia, Chiné Alessandra, Galli Cecilia, Piccioni Maria G

Abstract excerpt

INTRODUCTION: BRCA1 and BRCA2 genes mutations seems to impact female fertility, in addition to increasing the risk of ovarian and breast cancer. Several studies had investigated this issue but data available are still controversial. In order to clarify the role of BRCA1 and BRCA2 mutations in female fertility and ovarian function we carried out a systematic review of the literature with the aim to establish a...

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PMID: 32744451
DOI: 10.23736/S0026-4784.20.04624-9

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