Article
Effects of BRCA gene mutation on female reproductive potential: A systematic review.
Maturitas - 1 Jul 2020
Hu Kai-Lun, Wang Siwen, Ye Xiaohang, Zhang Dan
Abstract excerpt
Mutation of BRCA genes significantly increases the lifetime risk of breast, ovarian, fallopian tube and primary peritoneal cancers. In addition to the increased risk of these multiple malignancies, the recent literature suggests that mutations in BRCA genes may lead to decreased reproductive potential. In this systematic review, we focus on the effect of BRCA gene mutation on reproductive potential. The main...
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