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Article

BRCA1 mutation carriers have a lower number of mature oocytes after ovarian stimulation for IVF/PGD.

Journal of assisted reproduction and genetics - 1 Nov 2017

Derks-Smeets I A P, van Tilborg T C, van Montfoort A, Smits L, Torrance H L, Meijer-Hoogeveen M, Broekmans F, Dreesen J C F M, Paulussen A D C, Tjan-Heijnen V C G, Homminga I, van den Berg M M J, Ausems M G E M, de Rycke M, de Die-Smulders C E M, Verpoest W, van Golde R

Abstract excerpt

PURPOSE: The aim of this study was to determine whether BRCA1/2 mutation carriers produce fewer mature oocytes after ovarian stimulation for in vitro fertilization (IVF) with preimplantation genetic diagnosis (PGD), in comparison to a PGD control group. METHODS: A retrospective, international, multicenter cohort study was performed on data of first PGD cycles performed between January 2006 and September 2015....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 28831696
DOI: 10.1007/s10815-017-1014-3
PMCID: PMC5699993

Genes

BRCA1
PGD
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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