Article
HLA Genotyping in Romanian Adult Patients with Celiac Disease, their First-degree Relatives and Healthy Persons.
Journal of gastrointestinal and liver diseases : JGLD - 12 Jun 2022
Maruntelu Ion, Preda Carmen Monica, Sandra Irina, Istratescu Doina, Chifulescu Andreea Elena, Manuc Mircea, Diculescu Mircea, Talangescu Adriana, Tugui Letitia, Manuc Teodora, Stroie Tudor, Andrei Adriana Corina, Tieranu Cristian, Constantinescu Ileana
Abstract excerpt
BACKGROUND AND AIMS: Celiac disease is characterized by an inappropriate T-cell-mediated response to gluten in small bowel in genetically predisposed individuals, carriers of the DQ2 and/or DQ8 haplotypes of the human leukocyte antigen. The aim of our study was to asses HLA typing in adult patients with celiac disease, in their first degree relatives and in a healthy control group. METHODS: We conducted a...
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