A Clinician's Guide to Celiac Disease HLA Genetics

doi:10.14309/ajg.0000000000000310

Article

A Clinician's Guide to Celiac Disease HLA Genetics

4 Jul 2019

Abstract excerpt

Celiac disease is a common inflammatory disease triggered by dietary gluten in genetically susceptible individuals. The strongest and best-characterized genetic susceptibilities in celiac disease are class II human leukocyte antigen (HLA) genes known as HLA-DQ2 and DQ8. HLA genetic testing is available through a number of commercial and academic laboratories and is used in the evaluation of celiac disease and to...

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