Article
Cannabis alters DNA methylation at maternally imprinted and autism candidate genes in spermatogenic cells
10 Jun 2022
Abstract excerpt
Cannabis use in the United States is increasing, with highest consumption among men at their peak reproductive years. We previously demonstrated widespread changes in sperm DNA methylation with cannabis exposure in humans and rats, including genes important in neurodevelopment. Here, we use an in vitro human spermatogenesis model to recapitulate chronic cannabis use and assess DNA methylation at imprinted and...
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