Back to search

Article

Tetrahydrocannabinol exposure to postejaculatory sperm compromises sperm structure, function, the epigenome, and early embryo development

2026-03-24

Abstract excerpt

Cannabis (marijuana) is the most widely used recreational drug in the USA accounting for about 62 million users in 2024. Among cannabis users, 26% are of prime reproductive age (18-25 years). Delta-9 tetrahydrocannabinol (THC) is the principal psychoactive component of cannabis and has been detected in human seminal fluids. Although abundant evidence indicates adverse effects of THC exposure on spermatogenesis in...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
4980670b-8b30-5780-97c4-b968ae6e4d38
DOI
10.64898/2026.03.23.713385
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Tetrahydrocannabinol exposure to postejaculatory sperm compromises sperm structure, function, the epigenome, and early embryo developmentDOI 10.64898/2026.03.23.713385
Sperm capacitation and transcripts levels are altered by in vitro THC exposureSemantic proximity
Cannabis use and the sperm epigenome: a budding concern?Semantic proximity
Expression of the endocannabinoid system and response to cannabinoid components by the human fetal testisSemantic proximity
Cannabis alters epigenetic integrity and endocannabinoid signalling in the human follicular nicheSemantic proximity
The manifold actions of endocannabinoids on female and male reproductive eventsSemantic proximity
Impacts of cannabinoid epigenetics on human development: reflections on Murphy et. al. ‘cannabinoid exposure and altered DNA methylation in rat and human sperm’ epigenetics 2018; 13: 1208-1221.Semantic proximity
Cannabinoid exposure and altered DNA methylation in rat and human spermSemantic proximity
Refraining from use diminishes cannabis-associated epigenetic changes in human spermSemantic proximity
Cannabis and Paternal Epigenetic InheritanceSemantic proximity
Endocannabinoids, sperm biology and human fertility☆Semantic proximity
The role of endocannabinoids in gonadal function and fertility along the evolutionary axisSemantic proximity
The Endocannabinoid System and Its Relationship to Human ReproductionSemantic proximity
Select a neighboring publication to make it the new centre.