Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Sperm DNA methylation epimutation biomarker for paternal offspring autism susceptibility.

Clinical epigenetics - 7 Jan 2021

Garrido Nicolás, Cruz Fabio, Egea Rocio Rivera, Simon Carlos, Sadler-Riggleman Ingrid, Beck Daniel, Nilsson Eric, Ben Maamar Millissia, Skinner Michael K

Abstract excerpt

BACKGROUND: Autism spectrum disorder (ASD) has increased over tenfold over the past several decades and appears predominantly associated with paternal transmission. Although genetics is anticipated to be a component of ASD etiology, environmental epigenetics is now also thought to be an important factor. Epigenetic alterations, such as DNA methylation, have been correlated with ASD. The current study was designed...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Autistic Disorder
Share to Biomarkers

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Methylation

Share to Epigenesis, Genetic

Share to Fathers

Share to Genetic Markers

Share to Spermatozoa

Source

Open in PubMed Open full text

Identifiers

PMID: 33413568
DOI: 10.1186/s13148-020-00995-2
PMCID: PMC7789568

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Sperm DNA methylation epimutation biomarker for paternal offspring autism susceptibility.PMID 33413568Read ↗

Age-specific DNA methylation alterations in sperm at imprint control regions may contribute to the risk of autism spectrum disorder in offspring.Semantic proximity Read ↗

Epigenetic Signatures in Family Clusters: Links Between Male Fertility and Autism Risk.Semantic proximity Read ↗

Elevated polygenic burden for autism is associated with differential DNA methylation at birthSemantic proximity Read ↗

DNA Methylation Biomarkers for Young Children with Idiopathic Autism Spectrum Disorder: A Systematic Review.Semantic proximity Read ↗

Peripheral blood DNA methylation and autism spectrum disorderSemantic proximity Read ↗

Autism risk in offspring can be assessed through quantification of male sperm mosaicism.Semantic proximity Read ↗

Single-Cell, Human Sperm Transcriptomes and Variants from Fathers of Autistic and Healthy ChildrenSemantic proximity Read ↗

Quantification of autism recurrence risk by direct assessment of paternal sperm mosaicismSemantic proximity Read ↗

Epigenomic strategies at the interface of genetic and environmental risk factors for autism.Semantic proximity Read ↗

Paternal age effects on sperm FOXK1 and KCNA7 methylation and transmission into the next generation.Semantic proximity Read ↗

Methylomic analysis of monozygotic twins discordant for autism spectrum disorder and related behavioural traits.Semantic proximity Read ↗

Haplotype-resolved methylomes reveal parent-of-origin DNA methylation imbalance in autism spectrum disorder.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.