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Article

Refraining from use diminishes cannabis-associated epigenetic changes in human sperm

1 Sept 2021

Abstract excerpt

Abstract Cannabis use alters sperm DNA methylation, but the potential reversibility of these changes is unknown. Semen samples from cannabis users and non-user controls were collected at baseline and again following a 77-day period of cannabis abstinence (one spermatogenic cycle). Users and controls did not significantly differ by demographics or semen analyses. Whole-genome bisulfite sequencing identified 163...

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PMID: 34557312
DOI: 10.1093/eep/dvab009

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