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Article

Cannabinoid exposure and altered DNA methylation in rat and human sperm

2 Dec 2018

Abstract excerpt

Little is known about the reproductive effects of paternal cannabis exposure. We evaluated associations between cannabis or tetrahydrocannabinol (THC) exposure and altered DNA methylation in sperm from humans and rats, respectively. DNA methylation, measured by reduced representation bisulfite sequencing, differed in the sperm of human users from non-users by at least 10% at 3,979 CpG sites. Pathway analyses...

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Share to Birth, Development, and Health
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 30521419
DOI: 10.1080/15592294.2018.1554521

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