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Article

Novel NTRK3 Fusions in Fibrosarcomas of Adults

5 Dec 2018

Abstract excerpt

NTRK fusions in malignant tumors are therapeutic targets of tyrosine kinase inhibitors. Because they occur only in a small subset of mesenchymal tumors, knowledge regarding the corresponding histology is important to effectively identify patients who could benefit from targeted therapy. In this study, using RNA sequencing, we identified novel NTRK3 fusions involving related partner genes in 2 adult bone and soft...

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PMID: 30520818
DOI: 10.1097/pas.0000000000001194

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