Article
NTRK gene fusions in solid tumors: agnostic relevance, prevalence and diagnostic strategies
1 Jun 2022
Abstract excerpt
A number of innovative drugs, developed for precision medicine, have shown impressive activity in neoplastic patients with rare molecular targets, independently from the site and type of tumor. This gave rise to the concept of agnostic treatments in oncology. The detection of such rare targets is a prerequisite for these treatments and is nowadays one of the main challenges in diagnostic molecular pathology....
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