Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Hypergastrinemia, a clue leading to the identification of an atypical form of diabetes mellitus type 2.

Clinica chimica acta; international journal of clinical chemistry - 1 Jul 2022

Steyaert Wouter, Varney Matthew J, Benovic Jeffrey L, Creemers John, Speeckaert Marijn M, Coucke Paul J, Delanghe Joris R

Abstract excerpt

BACKGROUND: A hitherto undescribed form of diabetes mellitus type 2 is reported in a Flemish family. In these patients, markedly elevated gastrin levels were observed, which could not be linked to gastrointestinal symptoms. MATERIALS AND METHODS: Gel permeation chromatography was performed for gastrin, insulin, and proinsulin. Proprotein convertase subtilisin/kexin type (PCSK1 and PCSK2)] were sequenced....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Base Sequence
Share to Diabetes Mellitus, Type 2

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gastrins

Share to Mammals

Share to Mutation

Share to Proinsulin

Source

Identifiers

PMID: 35623402
DOI: 10.1016/j.cca.2022.05.016

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Hypergastrinemia, a clue leading to the identification of an atypical form of diabetes mellitus type 2.PMID 35623402Read ↗

A common variant upstream of the PAX6 gene influences islet function in man.Semantic proximity Read ↗

Determinants of plasma levels of gcg and metabolic impact of glucagon receptor signalling – a UK Biobank studySemantic proximity Read ↗

Type 2 Diabetes Risk Alleles Reveal a Role for Peptidylglycine Alpha-amidating Monooxygenase in Beta Cell FunctionSemantic proximity Read ↗

Genetic and functional characterization of PCSK1.Semantic proximity Read ↗

Cutis laxa, exocrine pancreatic insufficiency and altered cellular metabolomics as additional symptoms in a new patient with ATP6AP1-CDGSemantic proximity Read ↗

A novel mutation of PCSK1 responsible for PC1/3 deficiency in two siblings.Semantic proximity Read ↗

Phenotypic Characterization of Congenital Hyperinsulinism Due to Novel Activating Glucokinase Mutations.Semantic proximity Read ↗

Functional and clinical relevance of novel and known PCSK1 variants for childhood obesity and glucose metabolism.Semantic proximity Read ↗

Non-insulinoma persistent hyperinsulinaemic hypoglycaemia caused by an activating glucokinase mutation: hypoglycaemia unawareness and attacks.Semantic proximity Read ↗

Wolfram syndrome 1 and adenylyl cyclase 8 interact at the plasma membrane to regulate insulin production and secretion.Semantic proximity Read ↗

Familial adult onset hyperinsulinism due to an activating glucokinase mutation: implications for pharmacological glucokinase activation.Semantic proximity Read ↗

Hyperphagia and Early-Onset Obesity due to a Novel Homozygous Missense Mutation in Prohormone Convertase 1/3Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.