Article
Cognitive and behavioural changes in PLS and PMA:challenging the concept of restricted phenotypes.
Journal of neurology, neurosurgery, and psychiatry - 1 Feb 2019
de Vries Bálint S, Rustemeijer Laura M M, Bakker Leonhard A, Schröder Carin D, Veldink Jan H, van den Berg Leonard H, Nijboer Tanja C W, van Es Michael A
Abstract excerpt
OBJECTIVES: Cognitive and behavioural changes within the spectrum of frontotemporal dementia (FTD) are observed frequently in patients with amyotrophic lateral sclerosis (ALS). Whether these changes also occur in other forms of motor neuron disease (MND) is not well studied. We therefore systemically screened a large cohort of patients with primary lateral sclerosis (PLS) and progressive muscular atrophy (PMA)...
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