Article
Variability and prognostic relevance of different phenotypes in amyotrophic lateral sclerosis - data from a population-based registry.
Journal of the neurological sciences - 15 Oct 2014
Wolf Joachim, Safer Anton, Wöhrle Johannes C, Palm Frederick, Nix Wilfred A, Maschke Matthias, Grau Armin J
Abstract excerpt
OBJECTIVES: The clinical spectrum of amyotrophic lateral sclerosis (ALS) is characterized by a considerable variation. Different phenotypes have been described by previous studies. We assessed clinical variability and prognostic relevance of these phenotypes in a prospective, population-based cohort of ALS patients in Rhineland-Palatinate, Germany. METHODS: Incident ALS cases, diagnosed between October 2009 and...
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