Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association Between Neddylation and Immune Response

5 May 2022

Abstract excerpt

the activation of the neural precursor cell expressed, developmentally downregulated protein 8 (NEDD8) by three enzymes: activating enzyme, conjugating enzyme, and ligase. NEDD8 was first isolated from the mouse brain in 1992 and was initially considered important for the development and differentiation of the central nervous system. Previously, the downregulation of neddylation was associated with some human...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Peptidase Inhibition and Analysis
Share to RNA modifications and cancer
Share to Ubiquitin and proteasome pathways

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 35602593
DOI: 10.3389/fcell.2022.890121

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association Between Neddylation and Immune ResponsePMID 35602593Read ↗

Neddylation plays an important role in the regulation of murine and human dendritic cell function.Semantic proximity Read ↗

Neddylation: A Versatile Pathway Takes on Chronic Liver DiseasesSemantic proximity Read ↗

K27-linked RORγt ubiquitination by Nedd4 potentiates Th17-mediated autoimmunitySemantic proximity Read ↗

Targeting protein neddylation: a novel therapeutic strategy for the treatment of cancerSemantic proximity Read ↗

The regulatory roles of the E3 ubiquitin ligase NEDD4 family in DNA damage responseSemantic proximity Read ↗

Cell type-specific transcriptomics identifies neddylation as a novel therapeutic target in multiple sclerosisSemantic proximity Read ↗

Targeting cullin neddylation for cancer and fibrotic diseasesSemantic proximity Read ↗

Unraveling the Potential Role of NEDD4-like E3 Ligases in CancerSemantic proximity Read ↗

Host Cell Neddylation Facilitates Alphaherpesvirus Entry in a Virus-Specific and Cell-Dependent MannerSemantic proximity Read ↗

Neddylation pathway alleviates chronic pancreatitis by reducing HIF1α-CCL5-dependent macrophage infiltration.Semantic proximity Read ↗

The NEDD8 Conjugation Pathway and Its Relevance in Cancer Biology and TherapySemantic proximity Read ↗

Immune regulatory functions of DOCK family proteins in health and disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.