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Neddylation: A Versatile Pathway Takes on Chronic Liver Diseases

19 Oct 2020

Abstract excerpt

Neddylation is a ubiquitin-like posttranslational modification that conjugates neural precursor cell expressed developmentally downregulated-8 (Nedd8) to specific substrates for regulation of protein activity. In light of current researches, the neddylation pathway is aberrant in the pathogenesis of many diseases. In our review, we summarize the versatile roles of neddylation in chronic liver diseases (CLDs)....

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PMID: 33195347
DOI: 10.3389/fmed.2020.586881

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