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The Role of H3K9 Acetylation and Gene Expression in Different Brain Regions of Alzheimer’s Disease Patients

19 May 2022

Abstract excerpt

Aims: To evaluate H3K9 acetylation and gene expression profiles in three brain regions of Alzheimer’s disease (AD) patients and elderly controls, and to identify AD region-specific abnormalities. Methods: Brain samples of auditory cortex, hippocampus and cerebellum from AD patients and controls underwent chromatin immunoprecipitation sequencing, RNA sequencing and network analyses. Results: We found a...

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PMID: 35588246
DOI: 10.2217/epi-2022-0096

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