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Glutamatergic dysfunction is associated with phenotypes of VGF-overexpressing mice.

Experimental brain research - 1 Aug 2022

Mizoguchi Takahiro, Fujimori Honoka, Ohba Takuya, Shimazawa Masamitsu, Nakamura Shinsuke, Shinohara Masakazu, Hara Hideaki

Abstract excerpt

VGF nerve growth factor inducible (VGF) is a neuropeptide precursor, which is induced by several neurotrophic factors, including nerve growth factor and brain-derived neurotrophic factor. Clinically, an upregulation of VGF levels has been reported in the cerebrospinal fluid and prefrontal cortex of patients with schizophrenia. In our previous study, mice overexpressing VGF exhibited schizophrenia-related...

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PMID: 35587282
DOI: 10.1007/s00221-022-06384-w

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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