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Article

Gibbin mesodermal regulation patterns epithelial development.

Nature - 1 Jun 2022

Collier Ann, Liu Angela, Torkelson Jessica, Pattison Jillian, Gaddam Sadhana, Zhen Hanson, Patel Tiffany, McCarthy Kelly, Ghanim Hana, Oro Anthony E

Abstract excerpt

Proper ectodermal patterning during human development requires previously identified transcription factors such as GATA3 and p63, as well as positional signalling from regional mesoderm1-6. However, the mechanism by which ectoderm and mesoderm factors act to stably pattern gene expression and lineage commitment remains unclear. Here we identify the protein Gibbin, encoded by the Xia-Gibbs AT-hook...

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Identifiers

PMID: 35585237
DOI: 10.1038/s41586-022-04727-9
PMCID: PMC9202145

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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