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Article

Hepatitis B virus splicing is enhanced prior to development of hepatocellular carcinoma.

Journal of hepatology - 1 Nov 2013

Bayliss Julianne, Lim Lucy, Thompson Alexander J V, Desmond Paul, Angus Peter, Locarnini Stephen, Revill Peter A

Abstract excerpt

BACKGROUND & AIMS: The hepatitis B virus (HBV) genome encodes specific sequence elements which promote splicing of viral DNA. It has been previously suggested that spliced HBV (spHBV) variants promote viral replication and protein production, leading to hepatocellular carcinoma (HCC). In this stu...

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Share to Carcinoma, Hepatocellular
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 23811301
DOI: 10.1016/j.jhep.2013.06.018

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23811301-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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