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Article

Unique intrahepatic transcriptomics profiles discriminate the clinical phases of a chronic HBV infection

29 Jun 2017

Abstract excerpt

Chronic hepatitis B is a highly heterogeneous liver disease characterized by phases with fluctuations in viral replication and progressive liver damage in some, but not all infected individuals. Despite four decades of research, insight into host determinants underlying these distinct clinical phases-immunotolerant, immune active, inactive carrier, and HBeAg-negative hepatitis-remains elusive. We performed an...

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PMID: 28662087
DOI: 10.1371/journal.pone.0179920

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