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Article

Differential association of ESR1 and ESR2 gene variants with the risk of breast cancer and associated features: A case-control study.

Gene - 20 Apr 2018

Ghali Rabeb M, Al-Mutawa Maryam A, Al-Ansari Abrar K, Zaied Sonia, Bhiri Hanen, Mahjoub Touhami, Almawi Wassim Y

Abstract excerpt

BACKGROUND: Estrogen is key to breast cancer pathogenesis, and acts by binding its receptor (ER), which exists as ERα and ERβ, encoded by ESR1 and ESR2 genes, respectively. Studies that investigated the association of ESR1 and ESR2 variants with breast cancer yielded mixed outcome, and ethnic contribution was proposed. We evaluated the association between ESR1 and ESR2 variants and breast cancer and associated...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 29414691
DOI: 10.1016/j.gene.2018.02.011

Genes

ESR1
ESR2
MAF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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