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CT Radiomics-Clinical Model for Noninvasive Prediction of Tumor Mutation Burden and Survival in Locally Advanced Head and Neck Squamous Cell Carcinoma

2025-07-22

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<title>Abstract</title> <p>Purpose Tumor mutation burden (TMB) has emerged as a promising biomarker for predicting immunotherapy response. This study aimed to evaluate the potential of a CT-based radiomics model to predict TMB status and overall survival (OS) in patients with head and neck squamous cell carcinoma (HNSCC). Methods Somatic mutation and transcriptome data of 506 HNSCC cases were retrieved from The C...

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Literature Corpus work
ae0dd4dd-00aa-55f5-9514-d27dd096fe8f
DOI
10.21203/rs.3.rs-6921523/v1
Open publication

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