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Article

Comprehensive genomic profiling of different subtypes of nasopharyngeal carcinoma reveals similarities and differences to guide targeted therapy.

Cancer - 15 Sept 2017

Ali Siraj M, Yao Ming, Yao Jicheng, Wang Jing, Cheng Yuwei, Schrock Alexa B, Chirn Gung-Wei, Chen Hui, Mu Shuo, Gay Laurie, Elvin Julia A, Suh James, Miller Vincent A, Stephens Philip J, Ross Jeffrey S, Wang Kai

Abstract excerpt

BACKGROUND: To date, no targeted therapy has been approved for nasopharyngeal carcinoma (NPC), and this underscores the need for an in-depth understanding of clinically relevant genomic alterations (CRGAs). METHODS: Comprehensive genomic profiling was performed for 190 NPC patients, including 20 patients with nasopharyngeal adenocarcinoma (NPAC), 62 patients with nasopharyngeal squamous cell carcinoma (NPSCC),...

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Identifiers

PMID: 28581676
DOI: 10.1002/cncr.30781

Genes

IDH2
CCND1
EGFR
KRAS
NOTCH1
PTEN
SMARCB1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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