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Whole exome sequencing and transcriptome-wide profiling identify potentially subtype-relevant genes of nasopharyngeal carcinoma.

Pathology, research and practice - 1 Dec 2020

Liu Ji, Li Xu, Yang Shanshan, Mou Junjun, Lu Haijun

Abstract excerpt

BACKGROUND: To date, no targeted therapy has been approved for nasopharyngeal carcinoma (NPC), suggesting that comprehensive understanding of genomic changes turns out to be an urgent need to break through the calm of currently known therapies of NPC. METHODS: Whole exome sequencing (WES) was performed for 14 NPC patients, including 6 NPC-IIA cases, 8 NPC-IIB cases. The cancer chip expression data named GSE12452...

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Biomarkers, Tumor
Exome Sequencing
Gene Expression Regulation, Neoplastic
Gene Regulatory Networks
Nasopharyngeal Carcinoma

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Nasopharyngeal Neoplasms

Protein Interaction Maps

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PMID: 33113455
DOI: 10.1016/j.prp.2020.153244

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