Article

Development of an accessible gene expression bioinformatics pipeline to study driver mutations of colorectal cancer

2021-11-15

Abstract excerpt

Colorectal cancer (CRC) is a global cause of cancer-related mortality driven by genetic and environmental factors which influence therapeutic outcomes. The emergence of next-generation sequencing technologies enables the rapid and extensive collection and curation of genetic data for each cancer type into clinical gene expression biobanks. In this study we used a combination of bioinformatics tools to investigate...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: a818c176-a9f9-507e-a282-7b71dbf2bf9d
DOI: 10.1101/2021.11.10.21266196

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Development of an accessible gene expression bioinformatics pipeline to study driver mutations of colorectal cancerDOI 10.1101/2021.11.10.21266196Read

Development of an Accessible Gene Expression Bioinformatics Pipeline to Study Driver Mutations of Colorectal Cancer.Semantic proximity Read

Whole genome sequencing of 2,023 colorectal cancers reveals mutational landscapes, new driver genes and immune interactionsSemantic proximity Read

A molecular signature for oncogenic BRAF in human colon cancer cells is revealed by microarray analysis.Semantic proximity Read

Genomics and epigenomics of colorectal cancerSemantic proximity Read

Comprehensive functional genomic analyses link APC somatic mutation and mRNA-miRNA networks to the clinical outcome of stage-III colorectal cancer patients.Semantic proximity Read

A multigene mutation classification of 468 colorectal cancers reveals a prognostic role for APC.Semantic proximity Read

The Role of Proteomics and Genomics in the Development of Colorectal Cancer Diagnostic Tools and Potential New TreatmentsSemantic proximity Read

Comprehensive genomic profiling reveals prognostic signatures and insights into the molecular landscape of colorectal cancerSemantic proximity Read

Mutation analysis of adenomas and carcinomas of the colon: Early and late drivers.Semantic proximity Read

Driver Gene Mutations and Epigenetics in Colorectal CancerSemantic proximity Read