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Article

Effect of non-contacted bases on the affinity of 434 operator for 434 repressor and Cro.

Nature - 1 Jan 2000

Koudelka G B, Harrison S C, Ptashne M

Abstract excerpt

The repressor of phage 434 binds to six operator sites on the phage chromosome. A comparison of the sequences of these 14-base-pair (bp) operator sites reveals a striking pattern: at five of the six sites, the symmetrically arrayed outer eight base pairs (four in each half-site) are identical and...

Topics

Base Sequence
Coliphages
DNA, Bacterial
Escherichia coli
Genes, Bacterial
Mutation
Operator Regions, Genetic
Protein Binding
Repressor Proteins
Transcription Factors
Viral Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 3553960
DOI: 10.1038/326886a0

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-3553960-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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