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Article

Differential recognition of OR1 and OR3 by bacteriophage 434 repressor and Cro.

The Journal of biological chemistry - 15 Nov 1993

Koudelka G B, Lam C Y

Abstract excerpt

The developmental decisions of bacteriophage 434 depend on the ability of 434 repressor and Cro to bind OR1 and OR3 with different relative affinities; repressor binds OR1 tighter than OR3, whereas Cro slightly prefers OR3 over OR1. Studies with operator mutants show that repressor's lower relati...

Topics

Amino Acids
Bacteriophages
Base Sequence
DNA
DNA-Binding Proteins
Molecular Sequence Data
Mutation
Operator Regions, Genetic
Repressor Proteins
Transcription Factors
Viral Proteins
Viral Regulatory and Accessory Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 8226917

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8226917-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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Differential recognition of OR1 and OR3 by bacteriophage 434 repressor and Cro.PMID 8226917Read ↗

DNA sequence requirements for the activation of 434 P(RM) transcription by 434 repressor.Semantic proximity Read ↗

Effect of non-contacted bases on the affinity of 434 operator for 434 repressor and Cro.Semantic proximity Read ↗

Repression of transcription initiation at 434 P(R) by 434 repressor: effects on transition of a closed to an open promoter complex.Semantic proximity Read ↗

Combinatorial redesign of the DNA binding specificity of a prokaryotic helix-turn-helix repressor.Semantic proximity Read ↗

Role of the Cro repressor carboxy-terminal domain and flexible dimer linkage in operator and nonspecific DNA binding.Semantic proximity Read ↗

Shared operator recognition specificity between Trp repressor and the repressors of bacteriophage 434.Semantic proximity Read ↗

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New Insights into the Phage Genetic Switch: Effects of Bacteriophage Lambda Operator Mutations on DNA Looping and Regulation of PR, PL, and PRM.Semantic proximity Read ↗

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