Article
Canonical transformation for multivariate mixed model association analyses.
TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik - 1 Jun 2022
Yang Li'ang, Zhang Ying, Song Yuxin, Zhang Hengyu, Yang Runqing
Abstract excerpt
KEY MESSAGE: In extension of Single-RunKing to analyze multiple correlated traits, mvRunKing not only enlarged number of the analyzed phenotypes with canonical transformation, but also improved statistical power to detect pleiotropic QTNs through joint association analysis. Based on genomic variance-covariance matrices, we simplified multivariate mixed model association analysis to multiple univariate ones by...
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