Article
A compressed variance component mixed model for detecting QTNs and QTN-by-environment and QTN-by-QTN interactions in genome-wide association studies.
Molecular plant - 4 Apr 2022
Li Mei, Zhang Ya-Wen, Zhang Ze-Chang, Xiang Yu, Liu Ming-Hui, Zhou Ya-Hui, Zuo Jian-Fang, Zhang Han-Qing, Chen Ying, Zhang Yuan-Ming
Abstract excerpt
Although genome-wide association studies are widely used to mine genes for quantitative traits, the effects to be estimated are confounded, and the methodologies for detecting interactions are imperfect. To address these issues, the mixed model proposed here first estimates the genotypic effects for AA, Aa, and aa, and the genotypic polygenic background replaces additive and dominance polygenic backgrounds. Then,...
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