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Article

Mutations in G6PC2 gene with increased risk for development of type 2 diabetes: Understanding via computational approach.

Advances in protein chemistry and structural biology - 1 Jan 2022

Udhaya Kumar S, Kamaraj Balu, Varghese Rinku Polachirakkal, Preethi V Anu, Bithia R, George Priya Doss C

Abstract excerpt

An increase in the fast blood glucose (FBG) levels has been linked to an increased risk of developing a chronic condition, type 2 diabetes (T2D). The mutation in the G6PC2 gene was identified to have a lead role in the modulation of FBG levels. The abnormal regulation of this enzyme influences glucose-stimulated insulin secretion (GSIS), which controls the insulin levels corresponding to the system's glucose...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Polymorphism, Single Nucleotide

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Identifiers

PMID: 35534112
DOI: 10.1016/bs.apcsb.2022.02.005

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