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Article

Age-specific effects of childhood body mass index on multiple sclerosis risk.

Journal of neurology - 1 Sept 2022

Hone Luke, Jacobs Benjamin M, Marshall Charles, Giovannoni Gavin, Noyce Alastair, Dobson Ruth

Abstract excerpt

OBJECTIVE: Higher body mass index (BMI) during early life is thought to be a causal risk factor for multiple sclerosis (MS). We used longitudinal Mendelian randomisation (MR) to determine whether there is a critical window during which BMI influences MS risk. METHODS: Summary statistics for childhood BMI (n ~ 28,000 children) and for MS susceptibility were obtained from recent large genome-wide association...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 35532785
DOI: 10.1007/s00415-022-11161-4
PMCID: PMC9363310

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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