Article
Early-Life Factors and Risk of Multiple Sclerosis: An MR-EWAS.
Neuroepidemiology - 1 Jan 2020
Belbasis Lazaros, Bellou Vanesa, Tzoulaki Ioanna, Evangelou Evangelos
Abstract excerpt
BACKGROUND: Although several risk factors are associated with multiple sclerosis (MS) in adulthood, evidence for risk factors acting from birth to adolescence is scarce. METHODS: We conceived a 2-step study design, where signals from an Environment-Wide Association Study are prioritized for follow-up in a Mendelian Randomization study (MR-EWAS), to examine the association of early-life factors with risk of MS....
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