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Article

Comprehensive and integrative analyses identify TYW5 as a schizophrenia risk gene.

BMC medicine - 9 May 2022

Zhang Chengcheng, Li Xiaojing, Zhao Liansheng, Liang Rong, Deng Wei, Guo Wanjun, Wang Qiang, Hu Xun, Du Xiangdong, Sham Pak Chung, Luo Xiongjian, Li Tao

Abstract excerpt

BACKGROUND: Identifying the causal genes at the risk loci and elucidating their roles in schizophrenia (SCZ) pathogenesis remain significant challenges. To explore risk variants associated with gene expression in the human brain and to identify genes whose expression change may contribute to the susceptibility of SCZ, here we report a comprehensive integrative study on SCZ. METHODS: We systematically integrated...

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Identifiers

PMID: 35527273
DOI: 10.1186/s12916-022-02363-8
PMCID: PMC9082878

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