Article
Common variants on 17q25 and gene-gene interactions conferring risk of schizophrenia in Han Chinese population and regulating gene expressions in human brain.
Molecular psychiatry - 1 Sept 2016
Guan L, Wang Q, Wang L, Wu B, Chen Y, Liu F, Ye F, Zhang T, Li K, Yan B, Lu C, Su L, Jin G, Wang H, Tian H, Wang L, Chen Z, Wang Y, Chen J, Yuan Y, Cong W, Zheng J, Wang J, Xu X, Liu H, Xiao W, Han C, Zhang Y, Jia F, Qiao X, Zhang D, Zhang M, Ma H
Abstract excerpt
Recently, two genome-wide association studies (GWASs) of schizophrenia (SCZ) in Han Chinese identified several susceptibility loci. Replication efforts aiming to validate the GWAS findings were made and focused on the top hits. We conducted a more extensive follow-up study in an independent sample of 1471 cases and 1528 matched controls to verify 26 genetic variants by including nine top single-nucleotide...
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