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Article

Performance of a high-throughput next-generation sequencing method for analysis of HIV drug resistance and viral load.

The Journal of antimicrobial chemotherapy - 1 Dec 2020

Fogel Jessica M, Bonsall David, Cummings Vanessa, Bowden Rory, Golubchik Tanya, de Cesare Mariateresa, Wilson Ethan A, Gamble Theresa, Del Rio Carlos, Batey D Scott, Mayer Kenneth H, Farley Jason E, Hughes James P, Remien Robert H, Beyrer Chris, Fraser Christophe, Eshleman Susan H

Abstract excerpt

OBJECTIVES: To evaluate the performance of a high-throughput research assay for HIV drug resistance testing based on whole genome next-generation sequencing (NGS) that also quantifies HIV viral load. METHODS: Plasma samples (n = 145) were obtained from HIV-positive MSM (HPTN 078). Samples were analysed using clinical assays (the ViroSeq HIV-1 Genotyping System and the Abbott RealTime HIV-1 Viral Load assay) and a...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 32772080
DOI: 10.1093/jac/dkaa352
PMCID: PMC7662169

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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