Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Does smoking protect against developing osteoarthritis? Evidence from a genetically informed perspective.

Seminars in arthritis and rheumatism - 1 Aug 2022

Ni Jing, Wang Peng, Yin Kang-Jia, Huang Ji-Xiang, Tian Tian, Cen Han, Sui Cong, Xu Zhiwei, Pan Hai-Feng

Abstract excerpt

OBJECTIVE: Cumulative evidence from observational studies showed an inverse association between smoking and osteoarthritis (OA), but this association could be confounded by obesity. This study aimed to decipher the causal effect of smoking on osteoarthritis risk from a genetically informed perspective. METHODS: We performed a two-sample univariable and multivariable MR to evaluate the independent effect of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Body Mass Index
Share to Genome-Wide Association Study

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mendelian Randomization Analysis

Share to Osteoarthritis, Hip

Share to Polymorphism, Single Nucleotide

Share to Risk Factors

Share to Smoking

Source

Identifiers

PMID: 35500427
DOI: 10.1016/j.semarthrit.2022.152013

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Does smoking protect against developing osteoarthritis? Evidence from a genetically informed perspective.PMID 35500427Read ↗

Genetics of osteoarthritis: Insights from GWAS to therapeutic opportunities.Semantic proximity Read ↗

Causal association between smoking behavior and the decreased risk of osteoarthritis: a Mendelian randomization.Semantic proximity Read ↗

Cardiometabolic traits mediating the effect of education on osteoarthritis risk: a Mendelian randomization studySemantic proximity Read ↗

The Genetic Epidemiological Landscape of Hip and Knee Osteoarthritis: Where Are We Now and Where Are We Going?Semantic proximity Read ↗

Causal Relationships of General and Abdominal Adiposity on Osteoarthritis: A Two-Sample Mendelian Randomization StudySemantic proximity Read ↗

A sex- and site-specific relationship between body mass index and osteoarthritis: evidence from observational and genetic analyses.Semantic proximity Read ↗

Associations of healthy lifestyle and genetic susceptibility with risks of osteoarthritis: a prospective cohort study.Semantic proximity Read ↗

Causal Association of Coffee Consumption and Total, Knee, Hip and Self-Reported Osteoarthritis: A Mendelian Randomization Study.Semantic proximity Read ↗

Translating osteoarthritis genetics research: challenging times ahead.Semantic proximity Read ↗

Uncovering causal genetic mediators linking redefined obesity to osteoarthritis: Multidimensional analysis from population to genetic mechanisms.Semantic proximity Read ↗

Potential Metabolic Pathways Linking Alcohol Consumption to Osteoarthritis: A Mediation Analysis of Plasma LipidsSemantic proximity Read ↗

The Genetics of Osteoarthritis: A ReviewSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.