Article
Causal Association of Coffee Consumption and Total, Knee, Hip and Self-Reported Osteoarthritis: A Mendelian Randomization Study.
Frontiers in endocrinology - 1 Jan 2021
Zhang Yangchang, Fan Jun, Chen Li, Xiong Yang, Wu Tingting, Shen Shisi, Wang Xu, Meng Xuchen, Lu Yanjun, Lei Xun
Abstract excerpt
Background: The causal association between coffee consumption and the risk of OA is limited. This study was conducted to identify the potential causal effects of coffee consumption on total, knee, hip, and self-reported OA. Methods: Genome-wide association studies (GWAS) of OA were derived from the UK Biobank, comprising 50,508 participants of European ancestry (10,083 with cases and 40,425 controls), and genetic...
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