Illuminating Clustered Mutations in Cancer.

Abstract excerpt

In mapping the landscape of clustered somatic mutations, researchers have found that such clusters are enriched on driver oncogenes and associated with differential survival. They also reported the prevalence of a particular cluster pattern, kataegis, on extrachromosomal DNA, describing it as kyklonas, potentially a new mode of cancer evolution.

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Mutation
• Share to Neoplasms
• Share to Oncogenes