Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association between single nucleotide polymorphisms in non-coding regions of the insulin (INS) gene and schizophrenia.

Neuro endocrinology letters - 1 Apr 2022

Melkersson Kristina, Persson Bengt

Abstract excerpt

OBJECTIVES: Schizophrenia is a psychotic disorder with high heritability. There are also indications that impaired cellular signalling via the insulin receptor-A and the insulin-like growth factor 1 receptor may play a role in its pathogenesis. Insulin, and possibly also C-peptide, are ligands to these receptors. The insulin gene, coding both insulin and C-peptide, has however not been genetically studied in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Gene Frequency
Share to C-Peptide
Share to Diabetes Mellitus, Type 1

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Predisposition to Disease

Share to Genotype

Share to Insulin

Share to Polymorphism, Single Nucleotide

Share to Schizophrenia

Source

Identifiers

PMID: 35490421

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association between single nucleotide polymorphisms in non-coding regions of the insulin (INS) gene and schizophrenia.PMID 35490421Read ↗

Glucose and Insulin-Related Traits, Type 2 Diabetes and Risk of Schizophrenia: A Mendelian Randomization Study.Semantic proximity Read ↗

The insulin receptor substrate-4 (IRS-4) gene and schizophrenia: no evidence for a main genetic factor, however one report of a single schizophrenia patient with a mutation.Semantic proximity Read ↗

Candidate gene association study in type 2 diabetes indicates a role for genes involved in beta-cell function as well as insulin action.Semantic proximity Read ↗

Association testing of common variants in the insulin receptor substrate-1 gene (IRS1) with type 2 diabetes.Semantic proximity Read ↗

Evidence for a negative association between schizophrenia and a polymorphism in the insulin receptor substrate-3 (IRS-3) gene.Semantic proximity Read ↗

Association of Insulin Resistance With Schizophrenia Polygenic Risk Score and Response to Antipsychotic TreatmentSemantic proximity Read ↗

Single nucleotide polymorphisms within functional regions of genes implicated in insulin action and association with the insulin resistant phenotype.Semantic proximity Read ↗

Dense mapping of the region of insulin gene VNTR in polycystic ovary syndrome in a population of women from Central Europe.Semantic proximity Read ↗

The type 2 diabetes mellitus susceptibility gene IGF2BP2 is associated with schizophrenia in a Han Chinese population.Semantic proximity Read ↗

Polymorphisms of INSIG2, MC4R, and LEP Are Associated With Obesity- and Metabolic-Related Traits in Schizophrenic PatientsSemantic proximity Read ↗

The potential shared role of inflammation in insulin resistance and schizophrenia: A bidirectional two-sample mendelian randomization study.Semantic proximity Read ↗

Microsatellite and Single Nucleotide Polymorphisms in the Insulin-Like Growth Factor 1 Promoter with Insulin Sensitivity and Insulin Secretion.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.