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Article

MYC-Driven Pathways in Breast Cancer Subtypes

11 Jul 2017

Abstract excerpt

The transcription factor MYC (MYC proto-oncogene, bHLH transcription factor) is an essential signaling hub in multiple cellular processes that sustain growth of many types of cancers. MYC regulates expression of RNA, both protein and non-coding, that control central metabolic pathways, cell death, proliferation, differentiation, stress pathways, and mechanisms of drug resistance. Activation of MYC has been widely...

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PMID: 28696357
DOI: 10.3390/biom7030053

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