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Identification of biomarker associated with Trop2 in breast cancer: implication for targeted therapy

6 Sept 2024

Abstract excerpt

PURPOSE: Trop2, a cell membrane glycoprotein, is overexpressed in almost all epithelial cancers. This study aimed to explore the mutational characteristics and significance of Trop2 in breast cancer (BC). METHODS: Patients diagnosed with BC (n = 77) were enrolled to investigate expression level and clinical characteristics of Trop2. Database of cBioPortal and Kaplan-Meier Plotter were used to evaluate the effects...

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PMID: 39240479
DOI: 10.1007/s12672-024-01261-0

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