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Article

Translocator protein (18 kDa) regulates the microglial phenotype in Parkinson's disease through P47.

Bioengineered - 1 Apr 2022

Xue Xue, Duan Rui, Zheng Guoyan, Chen Hucheng, Zhang Weiwei, Shi Liang

Abstract excerpt

Numerous studies have suggested that the phenotypic transformation of microglia plays a role in the pathogenesis of Parkinson's disease (PD). Translocator protein (TSPO) is an 18 kDa translocator membrane protein that acts as a marker of neuroinflammation and suppresses neuroinflammation; however, its underlying mechanism remains unclear. Although TSPO ligands were found to be protective in several...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 35475466
DOI: 10.1080/21655979.2022.2068754
PMCID: PMC9208449

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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