Article
Integration of Infant Metabolite, Genetic, and Islet Autoimmunity Signatures to Predict Type 1 Diabetes by Age 6 Years.
The Journal of clinical endocrinology and metabolism - 14 Jul 2022
Webb-Robertson Bobbie-Jo M, Nakayasu Ernesto S, Frohnert Brigitte I, Bramer Lisa M, Akers Sarah M, Norris Jill M, Vehik Kendra, Ziegler Anette-G, Metz Thomas O, Rich Stephen S, Rewers Marian J
Abstract excerpt
CONTEXT: Biomarkers that can accurately predict risk of type 1 diabetes (T1D) in genetically predisposed children can facilitate interventions to delay or prevent the disease. OBJECTIVE: This work aimed to determine if a combination of genetic, immunologic, and metabolic features, measured at infancy, can be used to predict the likelihood that a child will develop T1D by age 6 years. METHODS: Newborns with human...
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