Article
SpolPred: rapid and accurate prediction of Mycobacterium tuberculosis spoligotypes from short genomic sequences.
Bioinformatics (Oxford, England) - 15 Nov 2012
Coll Francesc, Mallard Kim, Preston Mark D, Bentley Stephen, Parkhill Julian, McNerney Ruth, Martin Nigel, Clark Taane G
Abstract excerpt
SUMMARY: Spoligotyping is a well-established genotyping technique based on the presence of unique DNA sequences in Mycobacterium tuberculosis (Mtb), the causal agent of tuberculosis disease (TB). Although advances in sequencing technologies are leading to whole-genome bacterial characterization, tens of thousands of isolates have been spoligotyped, giving a global view of Mtb strain diversity. To bridge the gap,...
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