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Article

Spoligotype signatures in the Mycobacterium tuberculosis complex.

Journal of clinical microbiology - 1 Jan 2007

Streicher E M, Victor T C, van der Spuy G, Sola C, Rastogi N, van Helden P D, Warren R M

Abstract excerpt

Evolution of the direct repeat region in Mycobacterium tuberculosis has created unique spoligotype signatures specifically associated with IS6110-defined strain families. Spoligotyping signatures may enable the analysis of the strain population structure in different settings and will enable the rapid identification of strain families that acquire drug resistance or escape protective immunity in drug and vaccine...

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Identifiers

PMID: 17065260
DOI: 10.1128/JCM.01429-06
PMCID: PMC1828946

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