Article
Whole-genome-based Mycobacterium tuberculosis surveillance: a standardized, portable, and expandable approach.
Journal of clinical microbiology - 1 Jul 2014
Kohl Thomas A, Diel Roland, Harmsen Dag, Rothgänger Jörg, Walter Karen Meywald, Merker Matthias, Weniger Thomas, Niemann Stefan
Abstract excerpt
Whole-genome sequencing (WGS) allows for effective tracing of Mycobacterium tuberculosis complex (MTBC) (tuberculosis pathogens) transmission. However, it is difficult to standardize and, therefore, is not yet employed for interlaboratory prospective surveillance. To allow its widespread application, solutions for data standardization and storage in an easily expandable database are urgently needed. To address...
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