Article
Paraoxonase 2 gene C311S polymorphism is associated with a risk of large vessel disease stroke in a Polish population.
Cerebrovascular diseases (Basel, Switzerland) - 1 Jan 2007
Slowik Agnieszka, Wloch Dorota, Szermer Pawel, Wolkow Pawel, Malecki Maciej, Pera Joanna, Turaj Wojciech, Dziedzic Tomasz, Klimkowicz-Mrowiec Aleksandra, Kopec Grzegorz, Figlewicz Denise A, Szczudlik Andrzej
Abstract excerpt
BACKGROUND: Oxidative stress plays a role in atherosclerosis. Human paraoxonase (PON) gene products exhibit antioxidant properties. We studied the significance of the Q192R and M55L polymorphisms of the PON1 gene and the C311S polymorphism of the PON2 gene in different etiologies of ischemic stroke. METHODS: One hundred and thirty-six patients with large vessel disease (LVD) stroke, 140 with small vessel disease...
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